Side effects related to systemic cancer treatment: are we changing the Promethean experience with molecularly targeted therapies?
نویسنده
چکیده
198 CURRENT ONCOLOGY—VOLUME 15, NUMBER 4 Copyright © 2008 Multimed Inc. Educational service provided to physicians by an unrestricted grant from Sanofi-Aventis Introducing our new series of expert guest editorials reporting upon different aspects of practice. These are independently reviewed and supported by unrestricted educational grants from our colleagues in industry. I N V I T E D E D I T O R I A L
منابع مشابه
Hitting the target: where do molecularly targeted therapies fit in the treatment scheduling of neuroendocrine tumours?
Neuroendocrine tumours (NETs) are a rare and heterogeneous group of tumours whose incidence is increasing and their prevalence is now greater than that of any other upper gastrointestinal tumour. Diagnosis can be challenging, and up to 25% of patients present with metastatic disease. Following the recent FDA approval of two new molecularly targeted therapies for the treatment of advanced pancre...
متن کاملSystemic Targeted Alpha Radiotherapy for Cancer
Background: The fundamental principles of internal targeted alpha therapy for cancer were established many decades ago.The high linear energy transfer (LET) of alpha radiation to the targeted cancer cellscauses double strand breaks in DNA. At the same time, the short range radiation spares adjacent normal tissues. This targeted approach complements conventional external beam radiotherapy and ch...
متن کاملSystemic cancer therapy: achievements and challenges that lie ahead
In the last half of the century, advances in the systemic therapy of cancer, including chemotherapy, hormonal therapy, targeted therapy, and immunotherapy have been responsible for improvements in cancer related mortality in developed countries even as the population continues to age. Although such advancements have yet to benefit all cancer types, systemic therapies have led to an improvement ...
متن کاملCardiotoxicity of Molecularly Targeted Agents
Cardiac toxicity of molecularly targeted cancer agents is increasingly recognized as a significant side effect of chemotherapy. These new potent therapies may not only affect the survival of cancer cells, but have the potential to adversely impact normal cardiac and vascular function. Unraveling the mechanisms by which these therapies affect the heart and vasculature is crucial for improving dr...
متن کاملMolecularly Targeted Agents as Radiosensitizers in Cancer Therapy—Focus on Prostate Cancer
As our understanding of the molecular pathways driving tumorigenesis improves and more druggable targets are identified, we have witnessed a concomitant increase in the development and production of novel molecularly targeted agents. Radiotherapy is commonly used in the treatment of various malignancies with a prominent role in the care of prostate cancer patients, and efforts to improve the th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Current Oncology
دوره 15 شماره
صفحات -
تاریخ انتشار 2008